This application can be used to compute the GemPred score of Gemcitabine sensitivity in pancreatic adenocarcinoma using a whole-transcriptome profile.

Input

The required input is a whole-transcriptome gene expression profile. A unique gene expression value should be given for each provided gene symbol. The input data table must be structured as follow:

  • A first column that contains gene symbols
  • A second column that contains numeric gene expression values

An example of the required file format can be downloaded using the Download button

Reference whole transcriptome is a 3' RNAseq approach with upper-quartile log2 (+1) normalization.

Result

A reference-free (unref) and referenced score are given. The unref score is to be considered for any cases in which the whole-transcriptome profiling diverges, even slightly, from the original approach. The ref score and associated GemPred prediction, should only be considered when profiles where obtained using the exact same process than that of the original study.

Disclaimer

This application is provided 'as is', with all faults and without any express and implied warranty including without limitation the implied warranties of title, fitness for a particular purpose, merchantability and noninfringement.

GemPred is a research tool under development with For Research Use Only or similar labeling statement. Implementation of the results in a clinical setting is in the sole responsibility of the treating physician.